Seminar | Dr. Russel W. Driver | Department of Chemistry and Physics | NSU
C-H…O Hydrogen Bonds: Basic Studies to New Materials
Date: September 28, 2022
Time: 12:05 – 12:50 pm
Via Zoom: https://nova.zoom.us/j/98484738908?pwd=THRjVFlCVDdtR1hzQmNmVkFRTmpoUT09
About the Talk:
Cyclopropanoyl caps designed to form Ca-H…O hydrogen bonds were appended to the N termini of helical a/B-peptide foldamers and the conjugates subsequently self-assembled to form foldamer architectures (foldectures). In this combined analytical and computational investigation cyclopropanoyl capping was observed to markedly enhance foldecture self-assembly in recalcitrant substrates and direct formation of a conserved intermolecular N-H…O/Ca-H…O bond motif, regardless of peptide sequence or foldamer secondary structure.
About the Speaker:
Dr. Driver is an assistant professor in the Department of Chemistry and Physics. He holds a doctorate from the University of Queensland. His research centers on the high-resolution structural characterization of folded molecular architectures and how non-covalent interactions influence shape selection in self-assembling systems far from equilibrium.